Creative Biolabs Provides One-Stop Solutions for Anti-Membrane Protein sdAb Development

October 18 07:56 2019

New York, USA, October 18, 2019 Inspired by comprehensive understanding of single domain antibody (sdAb) discovery and development in these years, Creative Biolabs is competent for designing a specialized one-stop sdAb solutions that can properly recognize the target membrane protein for customers all over the world, which includes but are not limited to Antigen Design and Preparation, Immune sdAb Library.

 

Membrane protein plays active roles in various fundamental physiological and homeostatic processes, which have been proved excellent candidates for therapeutic targets. However, there also exist several limitations for the use of membrane proteins to produce qualified antibodies, such as the immunological tolerance, potential steric problems. To overcome these obstacles, scientists at Creative Biolabs have made every effort to use sdAb, a type of antibody featured by small size, high stability, and great penetrability, to develop a reliable one-stop anti-membrane protein sdAb solution.

 

For the sake of a foolproof antigen selection in the sdAb development project, the Ph.D. level team at Creative Biolabs is capable of preparing versatile plans in terms of clients’ specific needs. Typically, the project is launched with either in silico sequence of the targets or the provided antigens from clients and scientist will customize and prepare different antigen forms, including but not limited to soluble proteins, peptides, hapten, intact membrane protein, whole cell, DNA.

As a trustworthy partner engaged in sdAb field for years, Creative Biolabs can apply its exclusive Hi-Affi™ Phage Display Platform to generate proper sdAb libraries from different sources with maximized diversity and library capacity of 1012, tailoring the best library screening and binder validation procedures to select specific binders with high affinity around 10-8-10-12. Immune sdAb library, naïve sdAb Library, and synthetic sdAb Library are all available for a customized project, in which VHH or VNAR based single domain antibody libraries are constructed through immunized camel, llama, alpaca or even shark. Besides, Creative Biolabs also provides a series of premade sdAbs libraries in house with a shorter lead time.

 

In addition, based on years of experience in overcoming numerous challenging targets, Creative Biolabs also can design customized screening strategies for novel sdAb discovery, including but not limited to Solid-Phase Screening, Solution-Sorting Screening, Cell-based Screening, in vivo Screening, ex vivo Screening

 

“Our team is equipped with knowledgeable scientists, skillful technicians and cutting-edge technologies. So, we are confident to guarantee each clients a satisfying cooperation experience with a low cost and fast delivery.” Introduced by the senior scientist at Creative Biolabs.

 

 

More information on single domain antibody development can be reached at https://www.creative-biolabs.com/sdab.

 

 

About

As one of the well-recognized service providers, Creative Biolabs always sticks to the Customer-first Principle and goal-oriented philosophy to serve clients all over the world. The one-stop discovery platforms developed by Creative Biolabs enable the novel sdAb discovery as research tool, therapeutic candidate, or diagnostic reagent. From the target identification to the final IND-enabling, Creative Biolabs has the capability to enable customers to free up time for core work and project. Furthermore, the subsequent sdAb development and characterization services can further meet the diverse needs of customers.

 

Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-619-7922
Address:45-1 Ramsey Road
City: Shirley
State: New York
Country: United States
Website: https://www.creative-biolabs.com/sdab

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